منابع مشابه
Early nutrition, epigenetics, and cardiovascular disease.
PURPOSE OF REVIEW Here, we provide a summary of the current knowledge on the impact of early life nutrition on cardiovascular diseases that have emerged from studies in humans and experimental animal models. The involvement of epigenetic mechanisms in the Developmental Origins of Health and Disease will be discussed in relation to the implications for the heart and the cardiovascular system. ...
متن کاملEpigenetics and social context: implications for disparity in cardiovascular disease.
BACKGROUND Although it is well established that African Americans (AA) experience greater social stressors than non-Hispanic Whites (NHW), the extent to which early life adversity and cumulative social stressors such as perceived discrimination, neighborhood violence, subjective social status, and socioeconomic status contribute to disparity in coronary heart disease (CHD) and stroke between AA...
متن کاملCell Therapy in Cardiovascular Disease
Recently, cell therapy has sparked a revolution in ischemic heart disease that will in the future help clinicians to cure patients. Earlier investigations in animal models and clinical trials have suggested that positive paracrine effects such as neoangiogenesis and anti-apoptotic can improve myocardial function. In this regard the Royan cell therapy center designed a few trials in collaborat...
متن کاملAdvances in Genetics Cardiovascular Epigenetics
Epigenetics is the study of heritable alterations in phenotypes and gene expression that occur without changes in the DNA sequence. Epigenetic mechanisms are flexible genomic factors that not only can change genome function under exogenous influence, but also can provide a molecular substrate that allows for the stable propagation of gene expression states from one generation of cells to the ne...
متن کاملCurrent genetics and epigenetics of smoking/tobacco-related cardiovascular disease.
Genetic and epigenetic factors are of great importance in cardiovascular biology and disease. Tobacco-smoking, one of the most important cardiovascular risk factors, is itself partially determined by genetic background and is associated with altered epigenetic patterns. This could render the genetics and epigenetics of smoking-related cardiovascular disease a textbook example of environmental e...
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ژورنال
عنوان ژورنال: Current Opinion in Cardiology
سال: 2011
ISSN: 0268-4705
DOI: 10.1097/hco.0b013e328345986e